Individual report to submitting centre (for research use only!)
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- Results of Staphylococcus aureus culture (positive/negative)
- Results of mecA PCR
- Results of PVL PCR
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Abstracts, presentations, congresses
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- ISSSI presentation Lyon 2012
- TropNet workshops Prague 2012, Hamburg 2014, Antwerp 2017
- ECCMID Barcelona 2014 & Vienna 2017
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Key findings that evolved from the StaphTrav collaboration are
Panton-Valentine leukocidine (PVL)
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- PVL is common in S. aureus imported from the tropics and subtropics (Zanger, CID 2012)
- PVL greatly increases the risk of recurrence and hospital admission in S. aureus-positive, travel-associated SSTIs (Nurjadi, CMI 2015)
- PVL predicts multi-resistance in imported S. aureus (Nurjadi, CIM 2015)
- PVL predicts resistance to TMP/SMZ in S. aureus (Zanger, CID 2012)
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MRSA imported by intercontinental travel
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- MRSA USA300 is the most commonly imported CA-MRSA clone and frequently acquired in Latin-America (poster, ESCMID Vienna 2017)
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Antimicrobial resistance in S. aureus causing travel-related SSTI
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- Multi-resistance is more common in isolates imported from South- and Southeast Asia (Nurjadi, CMI 2015)
- TMP/SMZ resistance in imported S. aureus is predominantly mediated by resistance gene dfrG (Nurjadi JAC 2014, Nurjadi, CMI 2015)
- Patterns of multi-resistance among imported aureus vary greatly by geographic exposure (Nurjadi, CMI 2015)
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Publications
Nurjadi D, Schäfer J, Friedrich-Jänicke B, Mueller A, Neumayr A, Calvo-Cano A, Goorhuis A, Molhoek N, Lagler H, Kantele A, Van Genderen PJ, Gascon J, Grobusch MP, Caumes E, Hatz C, Fleck R, Mockenhaupt FP, Zanger P (2015)
Predominance of dfrG as determinant of trimethoprim resistance in imported Staphylococcus aureus.
Clinical Microbiology and Infection 21:1095.e5-9. doi: 10.1016/j.cmi.2015.08.021.
Nurjadi D, Friedrich-Jänicke B, Schäfer J, Van Genderen PJ, Goorhuis A, Perignon A, Neumayr A, Mueller A, Kantele A, Schunk M, Gascon J, Stich A, Hatz C, Caumes E, Grobusch MP, Fleck R, Mockenhaupt FP, Zanger P (2015)
Skin and soft tissue infections in intercontinental travellers and the import of multi-resistant Staphylococcus aureus to Europe.
Clinical Microbiology and Infection 21:567.e1-10. doi: 10.1016/j.cmi.2015.01.016.
Zanger P (2014)
Methicillin-resistant Staphylococcus aureus and intercontinental travel –“bad bugs on the move!”
Journal of Travel Medicine 21:225-7. doi:10.1111/jtm.12140.
Nurjadi D, Olalekan AO, Layer F, Shittu AO, Alabi A, Ghebremedhin B, Schaumburg F, Hofmann-Eifler J, Van Genderen PJ, Caumes E, Fleck R, Mockenhaupt´FP, Herrmann M, Kern WV, Abdulla S, Grobusch MP, Kremsner PG, Wolz C, Zanger P (2014)
Emergence of trimethoprim resistance gene dfrG in Staphylococcus aureus causing human infection and colonization in sub-Saharan Africa and its import to Europe.
Journal of Antimicrobicals and Chemotherapy 69:2361-8. doi: 10.1093/jac/dku174.
Zanger P, Nurjadi D, Schleucher R, Scherbaum H, Wolz C, Kremsner PG, Schulte B (2012)
Import and spread of Panton-Valentine Leukocidin-positive Staphylococcus aureus through nasal carriage and skin infections in travelers returning from the tropics and subtropics.
Clinical Infectious Diseases 54:483-92. doi: 10.1093/cid/cir822.